Retinoids Help Normalize KeratinizationAlthough the mechanism by which topical and systemic retinoids help restore acne follicles to a healthy state is unknown, it has been well demonstrated that they normalize keratinization within the infundibular region of the follicle, so that shed follicular cells slough to the surface of the skin rather than clump together and obstruct the pores.After exposure to retinoids, follicular cells actually turn over more rapidly than they would in a pre-acne state.Retinoic acid has a high affinity for the gamma retinoid receptors, which are believed to be integral to the pathogenesis of acne.In addition to their ability to reverse abnormal keratinization within the follicle, the topical retinoids - especially adapalene (Differin®), a naphthoic acid derivative - may have anti-inflammatory properties and thus may address two factors involved in the development of acne.
When a person ia considering the use of benzoyl peroxide, they find that they also have to use various facial washes as well as skin conditioner to balance any amount of dryness that happens through the use of this type of treatment. While the expense of acne light treatment devices are greater than the majority of over the counter treatment medications, if you factor in the expenses of the conditioners as well as the washes, they typically will end up being close to the same.
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